Frequency of acervulus's accumulation in human pineal glands in some diseases of public health importance
Department of General and Clinical Pathology, Medical University of Varna
The information on the genesis, frequency of accumulation and the association of acervulus with different pathological processes in the human pineal gland are scarce and inconclusive.
Objective: The aim of the present study is to find out the frequency of accumulation of acervulus in human pineal glands in cases of diseases with public health importance.
Methods: 106 human pineal glands were studied. They were grouped according to the cause of death as identified in the autopsy protocols in the following groups: cerebro-vascular disease (n=23 ), acute myocardial infarction (n=10), carcinoma with different localizations(n=15), diabetes mellitus(n=21) and chronic alcoholism(n=11). A control group included 26 cases who died as a result of acute asphyxia from hanging. Standard cuts from paraffin embedded tissue were made and colored with Hematoxilin & Eosin, Van Gieson, Azan.
Results: The frequency of accumulation of accervulus in the pineal glands in the control group was greater than reported in the literature. The frequency of accumulation of acervulus in the groups of cerebrovascular diseases (95.7 %), acute myocardial infarction (100 %) and carcinoma with different localizations (93.3 %) was significantly higher than in the control group. No significant difference was observed between the frequency of accumulation of acervulus in the controls (69.2 %) and the groups of diabetes mellitus and chronic acoholism.
Sixth international symposium of clinical anatomy Varna, october 08th - 10th, 2004 Scr.Sci. Med Vol 36(2004) Supp.1 p.56
Adres for correspondence:
V. Dokov, Dept. of General and Clinical Pathology, Prof. P. Stoyanov
Medical University of Varna, 55 Marin Drinov St. BG-9002 Varna,